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BAY 2253651 for the treatment of obstructive sleep apnoea: a multicentre, double-blind, randomised controlled trial (SANDMAN)

Gaisl, Thomas; Turnbull, Chris D; Weimann, Gerrit; Unger, Sigrun; Finger, Rudolf; Xing, Charles; Cistulli, Peter A; West, Sophie; Chiang, Alan K I; Eckert, Danny J; Stradling, John R; Kohler, Malcolm (2021). BAY 2253651 for the treatment of obstructive sleep apnoea: a multicentre, double-blind, randomised controlled trial (SANDMAN). European Respiratory Journal, 58(5):2101937.

Abstract

BAY 2253651 is a nasally applied genioglossus muscle activator via pharyngeal mucosal receptor stimulation (potassium channel blocker) aimed to treat obstructive sleep apnoea. Although well-tolerated and safe, there was no significant therapeutic effect. https://bit.ly/3zDbyia

Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Pneumology
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Health Sciences > Pulmonary and Respiratory Medicine
Uncontrolled Keywords:Pulmonary and Respiratory Medicine
Language:English
Date:1 November 2021
Deposited On:10 Jan 2022 12:36
Last Modified:26 Oct 2024 01:41
Publisher:European Respiratory Society
ISSN:0903-1936
OA Status:Hybrid
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1183/13993003.01937-2021
PubMed ID:34531274
Project Information:
  • Funder: Bayer HealthCare
  • Grant ID:
  • Project Title:
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