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Open-source lab hardware: Low noise adjustable two-stage gain transimpedance amplifier with DC offset for low-light detection

Cretu, Vlad F; Kehl, Florian; Metz, Brandon C; Willis, Peter A (2021). Open-source lab hardware: Low noise adjustable two-stage gain transimpedance amplifier with DC offset for low-light detection. HardwareX, 10:e00233.

Abstract

An open-source, low noise, low cost, and tunable transimpedance amplifier is presented. The compact circuit board requires few parts and costs less than $65 USD. The transimpedance amplifier is intended for low-light detection and operation with commercial photomultiplier tubes (PMTs). It provides a much more cost-effective acquisition tool compared to competitive products on the market. The system can easily be assembled and modified to suit specific current sensing applications. The amplifier features two variable gains and an adjustable DC offset to optimize dynamic range and suppress potential bias in the signal. With a target bandwidth of DC to 2 Hz and fourth-order Sallen-Key cutoff, the design is ideally suited for various applications in the field of analytical chemistry and biology, such as laser-induced fluorescence detection or chemiluminescence measurements.

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Anatomy
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Scopus Subject Areas:Physical Sciences > Civil and Structural Engineering
Physical Sciences > Biomedical Engineering
Physical Sciences > Instrumentation
Physical Sciences > Mechanical Engineering
Physical Sciences > Industrial and Manufacturing Engineering
Language:English
Date:15 September 2021
Deposited On:08 Feb 2022 18:10
Last Modified:27 Dec 2024 02:36
Publisher:Elsevier
ISSN:2468-0672
OA Status:Gold
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1016/j.ohx.2021.e00233
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  • Content: Published Version
  • Language: English
  • Licence: Creative Commons: Attribution 4.0 International (CC BY 4.0)

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