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Marconi, Guya Diletta; Diomede, Francesca; Trubiani, Oriana; Porcheri, Cristina; Mitsiadis, Thimios A (2022). Exosomes as Carriers for Notch Molecules. In: Dongyu, Jia. Notch Signaling Research : Methods and Protocols. New York, NY: Springer, 197-208.
Exosomes are extracellular vesicles involved in cell-to-cell communication as well as extrusion of biological material. Using dental pulp stem cells culture as a model, we hereby describe a method for the packaging of Delta-like 4 (DLL4), a representative Notch ligand, into newly generated exosomes. We then provide methods of analysis to confirm the presence of Notch proteins and transcripts internalization and transport via exosomes.
| Item Type: | Book Section, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > Center for Dental Medicine > Institute of Oral Biology |
| Dewey Decimal Classification: | 610 Medicine & health |
| Scopus Subject Areas: | Life Sciences > Molecular Biology
Life Sciences > Genetics |
| Language: | English |
| Date: | 2022 |
| Deposited On: | 29 Jun 2022 11:24 |
| Last Modified: | 18 Mar 2025 04:44 |
| Publisher: | Springer |
| Series Name: | Methods in Molecular Biology |
| Number: | 2472 |
| ISSN: | 1064-3745 |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1007/978-1-0716-2201-8_16 |
| PubMed ID: | 35674902 |
| Other Identification Number: | eBook ISBN978-1-0716-2201-8 |
Marconi, Guya Diletta