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Feasibility of non-gated dynamic fetal cardiac MRI for identification of fetal cardiovascular anatomy


Geiger, Julia; Tuura, Ruth O Gorman; Callaghan, Fraser M; Burkhardt, Barbara Elisabeth Ursula; Kellenberger, Christian J; Valsangiacomo Buechel, Emanuela Regina (2023). Feasibility of non-gated dynamic fetal cardiac MRI for identification of fetal cardiovascular anatomy. Fetal Diagnosis and Therapy:Epub ahead of print.

Abstract

INTRODUCTION

To evaluate the feasibility of identifying the fetal cardiac and thoracic vascular structures with non-gated dynamic balanced steady-state free precession (SSFP) MRI sequences.

METHODS

We retrospectively assessed the visibility of cardiovascular anatomy in 60 fetuses without suspicion of congenital heart defect. Non-gated dynamic balanced SSFP sequences were acquired in three anatomic planes of the fetal thorax. The images were analyzed following a segmental approach in consensus reading by an experienced pediatric cardiologist and radiologist. An imaging score was defined by giving one point to each visualized structure, yielding a maximum score of 21 points. Image quality was rated from 0 (poor) to 2 (excellent). The influence of gestational age (GA), field strength, placenta position, and maternal panniculus on image quality and imaging score were tested.

RESULTS

30 scans were performed at 1.5T, 30 at 3T. Heart position, atria and ventricles could be seen in all 60 fetuses. Basic diagnosis (>12 points) was achieved in 54 cases. The mean imaging score was 16.8+/-3.8. Maternal panniculus (r=-0.3; p=0.015) and gestational age (r=0.6; p<0.001) correlated with imaging score. Field strength influenced image quality, with 1.5T being better than 3T images (p=0.012). Imaging score or quality were independent of placenta position.

DISCUSSION/CONCLUSION

Fetal cardiac MRI with non-gated SSFP sequences enables recognition of basic cardiovascular anatomy.

Abstract

INTRODUCTION

To evaluate the feasibility of identifying the fetal cardiac and thoracic vascular structures with non-gated dynamic balanced steady-state free precession (SSFP) MRI sequences.

METHODS

We retrospectively assessed the visibility of cardiovascular anatomy in 60 fetuses without suspicion of congenital heart defect. Non-gated dynamic balanced SSFP sequences were acquired in three anatomic planes of the fetal thorax. The images were analyzed following a segmental approach in consensus reading by an experienced pediatric cardiologist and radiologist. An imaging score was defined by giving one point to each visualized structure, yielding a maximum score of 21 points. Image quality was rated from 0 (poor) to 2 (excellent). The influence of gestational age (GA), field strength, placenta position, and maternal panniculus on image quality and imaging score were tested.

RESULTS

30 scans were performed at 1.5T, 30 at 3T. Heart position, atria and ventricles could be seen in all 60 fetuses. Basic diagnosis (>12 points) was achieved in 54 cases. The mean imaging score was 16.8+/-3.8. Maternal panniculus (r=-0.3; p=0.015) and gestational age (r=0.6; p<0.001) correlated with imaging score. Field strength influenced image quality, with 1.5T being better than 3T images (p=0.012). Imaging score or quality were independent of placenta position.

DISCUSSION/CONCLUSION

Fetal cardiac MRI with non-gated SSFP sequences enables recognition of basic cardiovascular anatomy.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:7 January 2023
Deposited On:13 Jan 2023 14:38
Last Modified:29 Jan 2023 11:36
Publisher:Karger
ISSN:1015-3837
OA Status:Hybrid
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1159/000528966
PubMed ID:36617416
  • Content: Accepted Version
  • Language: English