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Fernbach, Sonja; Hale, Benjamin G (2022). SARS-CoV-2 takes the bait: Exosomes as endogenous decoys. PLoS Biology, 20(9):e3001787.
Writing in PLOS Biology, Ching and colleagues show that ACE2-decorated exosomes are deployed as natural inhibitory decoys against SARS-CoV-2. High decoy levels correlate with improved patient outcomes, suggesting they directly help COVID-19 recovery and supporting the concept of successful future decoy-based therapies.
| Item Type: | Journal Article, refereed, further contribution |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > Institute of Medical Virology |
| Dewey Decimal Classification: | 570 Life sciences; biology
610 Medicine & health |
| Scopus Subject Areas: | Life Sciences > General Neuroscience
Life Sciences > General Biochemistry, Genetics and Molecular Biology Life Sciences > General Immunology and Microbiology Life Sciences > General Agricultural and Biological Sciences |
| Language: | English |
| Date: | September 2022 |
| Deposited On: | 17 Jan 2023 16:24 |
| Last Modified: | 29 Aug 2024 01:35 |
| Publisher: | Public Library of Science (PLoS) |
| ISSN: | 1544-9173 |
| OA Status: | Gold |
| Free access at: | PubMed ID. An embargo period may apply. |
| Publisher DOI: | https://doi.org/10.1371/journal.pbio.3001787 |
| PubMed ID: | 36103486 |
Fernbach, Sonja