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Interleukin-2–based therapies in cancer

Raeber, Miro E; Sahin, Dilara; Boyman, Onur (2022). Interleukin-2–based therapies in cancer. Science Translational Medicine, 14(670):abo5409.

Abstract

Molecular insights into the mechanism of beneficial and adverse effects of interleukin-2 (IL-2) have resulted in the development of improved IL-2 formulations with IL-2 receptor bias and tissue-targeting properties. Several of these compounds are currently in clinical development and are ushering IL-2 therapy into the current era of cancer immunotherapy.

Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Immunology
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Health Sciences > General Medicine
Uncontrolled Keywords:General Medicine
Language:English
Date:9 November 2022
Deposited On:01 Feb 2023 09:16
Last Modified:27 Jun 2025 01:35
Publisher:American Association for the Advancement of Science
ISSN:1946-6234
OA Status:Closed
Publisher DOI:https://doi.org/10.1126/scitranslmed.abo5409
PubMed ID:36350987
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