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Stress Urinary Incontinence: An Unsolved Clinical Challenge

Harland, Niklas; Walz, Simon; Eberli, Daniel; Schmid, Florian A; Aicher, Wilhelm K; Stenzl, Arnulf; Amend, Bastian (2023). Stress Urinary Incontinence: An Unsolved Clinical Challenge. Biomedicines, 11(9):2486.

Abstract

Stress urinary incontinence is still a frequent problem for women and men, which leads to pronounced impairment of the quality of life and withdrawal from the social environment. Modern diagnostics and therapy improved the situation for individuals affected. But there are still limits, including the correct diagnosis of incontinence and its pathophysiology, as well as the therapeutic algorithms. In most cases, patients are treated with a first-line regimen of drugs, possibly in combination with specific exercises and electrophysiological stimulation. When conservative options are exhausted, minimally invasive surgical therapies are indicated. However, standard surgeries, especially the application of implants, do not pursue any causal therapy. Non-absorbable meshes and ligaments have fallen into disrepute due to complications. In numerous countries, classic techniques such as colposuspension have been revived to avoid implants. Except for tapes in the treatment of stress urinary incontinence in women, the literature on randomized controlled studies is insufficient. This review provides an update on pharmacological and surgical treatment options for stress urinary incontinence; it highlights limitations and formulates wishes for the future from a clinical perspective.

Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Urological Clinic
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Health Sciences > Medicine (miscellaneous)
Life Sciences > General Biochemistry, Genetics and Molecular Biology
Language:English
Date:7 September 2023
Deposited On:05 Dec 2023 09:33
Last Modified:26 Mar 2025 04:35
Publisher:MDPI Publishing
ISSN:2227-9059
OA Status:Gold
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.3390/biomedicines11092486
PubMed ID:37760927
Other Identification Number:PMCID: PMC10525672
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  • Language: English
  • Licence: Creative Commons: Attribution 4.0 International (CC BY 4.0)

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