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ChatGPT, GPT-4, and Other Large Language Models: The Next Revolution for Clinical Microbiology?


Egli, Adrian (2023). ChatGPT, GPT-4, and Other Large Language Models: The Next Revolution for Clinical Microbiology? Clinical Infectious Diseases, 77(9):1322-1328.

Abstract

ChatGPT, GPT-4, and Bard are highly advanced natural language process-based computer programs (chatbots) that simulate and process human conversation in written or spoken form. Recently released by the company OpenAI, ChatGPT was trained on billions of unknown text elements (tokens) and rapidly gained wide attention for its ability to respond to questions in an articulate manner across a wide range of knowledge domains. These potentially disruptive large language model (LLM) technologies have a broad range of conceivable applications in medicine and medical microbiology. In this opinion article, I describe how chatbot technologies work and discuss the strengths and weaknesses of ChatGPT, GPT-4, and other LLMs for applications in the routine diagnostic laboratory, focusing on various use cases for the pre- to post-analytical process.

Abstract

ChatGPT, GPT-4, and Bard are highly advanced natural language process-based computer programs (chatbots) that simulate and process human conversation in written or spoken form. Recently released by the company OpenAI, ChatGPT was trained on billions of unknown text elements (tokens) and rapidly gained wide attention for its ability to respond to questions in an articulate manner across a wide range of knowledge domains. These potentially disruptive large language model (LLM) technologies have a broad range of conceivable applications in medicine and medical microbiology. In this opinion article, I describe how chatbot technologies work and discuss the strengths and weaknesses of ChatGPT, GPT-4, and other LLMs for applications in the routine diagnostic laboratory, focusing on various use cases for the pre- to post-analytical process.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Medical Microbiology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Scopus Subject Areas:Health Sciences > Microbiology (medical)
Health Sciences > Infectious Diseases
Uncontrolled Keywords:artificial intelligence; chatGPT; chatbot; digitalization; large language model
Language:English
Date:11 November 2023
Deposited On:18 Dec 2023 10:10
Last Modified:29 Jun 2024 01:41
Publisher:Oxford University Press
ISSN:1058-4838
OA Status:Hybrid
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1093/cid/ciad407
PubMed ID:37399030
  • Content: Published Version
  • Language: English
  • Licence: Creative Commons: Attribution 4.0 International (CC BY 4.0)