Navigation auf zora.uzh.ch

Search ZORA

ZORA (Zurich Open Repository and Archive)

Migration von ZORA auf die Software DSpace

ZORA will change to a new software on 8th September 2025. Please note: deadline for new submissions is 21th July 2025!

Information & dates for training courses can be found here: Information on Software Migration.

Investigation of ventricular cerebrospinal fluid flow phase differences between the foramina of Monro and the aqueduct of Sylvius

Schibli, M; Wyss, M; Boesiger, P; Guzzella, L (2009). Investigation of ventricular cerebrospinal fluid flow phase differences between the foramina of Monro and the aqueduct of Sylvius. Biomedizinische Technik. Biomedical Engineering, 54(4):161-169.

Abstract

In this paper, phase contrast magnetic resonance flow measurements of the foramina of Monro and the aqueduct of Sylvius of seven healthy volunteers are presented. Peak volume flow rates are of the order of 150 mm3/s for the aqueduct of Sylvius and for the foramina of Monro. The temporal shift between these volume flows is analyzed with a high-resolution cross-correlation scheme which reveals high subject-specific phase differences. Repeated measurements show the invariability of the phase differences over time for each volunteer. The phase differences as a fraction of one period range from -0.0537 to 0.0820. A mathematical model of the pressure dynamics is presented. The model features one lumped compartment per ventricle. The driving force of the cerebrospinal fluid is modeled through pulsating choroid plexus. The model includes variations of the distribution of the choroid plexus between the ventricles. The proposed model is able to reproduce the measured phase differences with a very small (5%) variation of the distribution of the choroid plexus between the ventricles and, therefore, supports the theory that the choroid plexus drives the cerebrospinal fluid motion.

Additional indexing

Other titles:Phasendifferenzen zwischen den Liquorströmungen im Aquädukt und in den Foramina Monro
Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Biomedical Engineering
Dewey Decimal Classification:170 Ethics
610 Medicine & health
Scopus Subject Areas:Physical Sciences > Biomedical Engineering
Language:English
Date:2009
Deposited On:02 Dec 2009 13:34
Last Modified:08 Jul 2025 03:33
Publisher:De Gruyter
ISSN:0013-5585
OA Status:Green
Publisher DOI:https://doi.org/10.1515/BMT.2009.021
PubMed ID:19614268
Download PDF  'Investigation of ventricular cerebrospinal fluid flow phase differences between the foramina of Monro and the aqueduct of Sylvius'.
Preview
  • Content: Published Version
  • Language: English
  • Description: Nationallizenz 142-005

Metadata Export

Statistics

Citations

Dimensions.ai Metrics
1 citation in Web of Science®
1 citation in Scopus®
Google Scholar™

Altmetrics

Downloads

210 downloads since deposited on 02 Dec 2009
9 downloads since 12 months
Detailed statistics

Authors, Affiliations, Collaborations

Similar Publications