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An Investigation of Stochastic Variance Reduction Algorithms for Relative Difference Penalized 3D PET Image Reconstruction

Twyman, Robert; Arridge, Simon; Kereta, Zeljko; Jin, Bangti; Brusaferri, Ludovica; Ahn, Sangtae; Stearns, Charles W; Hutton, Brian F; Burger, Irene A; Kotasidis, Fotis; Thielemans, Kris (2022). An Investigation of Stochastic Variance Reduction Algorithms for Relative Difference Penalized 3D PET Image Reconstruction. IEEE Transactions on Medical Imaging, 42(1):29-41.

Abstract

Penalised PET image reconstruction algorithms are often accelerated during early iterations with the use of subsets. However, these methods may exhibit limit cycle behaviour at later iterations due to variations between subsets. Desirable converged images can be achieved for a subclass of these algorithms via the implementation of a relaxed step size sequence, but the heuristic selection of parameters will impact the quality of the image sequence and algorithm convergence rates. In this work, we demonstrate the adaption and application of a class of stochastic variance reduction gradient algorithms for PET image reconstruction using the relative difference penalty and numerically compare convergence performance to BSREM. The two investigated algorithms are: SAGA and SVRG. These algorithms require the retention in memory of recently computed subset gradients, which are utilised in subsequent updates. We present several numerical studies based on Monte Carlo simulated data and a patient data set for fully 3D PET acquisitions. The impact of the number of subsets, different preconditioners and step size methods on the convergence of regions of interest values within the reconstructed images is explored. We observe that when using constant preconditioning, SAGA and SVRG demonstrate reduced variations in voxel values between subsequent updates and are less reliant on step size hyper-parameter selection than BSREM reconstructions. Furthermore, SAGA and SVRG can converge significantly faster to the penalised maximum likelihood solution than BSREM, particularly in low count data.

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Nuclear Medicine
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Physical Sciences > Software
Health Sciences > Radiological and Ultrasound Technology
Physical Sciences > Computer Science Applications
Physical Sciences > Electrical and Electronic Engineering
Language:English
Date:29 December 2022
Deposited On:29 Jan 2024 07:59
Last Modified:27 Feb 2025 02:37
Publisher:Institute of Electrical and Electronics Engineers
ISSN:0278-0062
OA Status:Hybrid
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1109/TMI.2022.3203237
PubMed ID:36044488
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  • Content: Published Version
  • Language: English
  • Licence: Creative Commons: Attribution 4.0 International (CC BY 4.0)

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