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Myths and methodologies: Cardiopulmonary exercise testing for surgical risk stratification in patients with an abdominal aortic aneurysm; balancing risk over benefit

Bailey, Damian M; Davies, Richard G; Rose, George A; Lewis, Michael H; Aldayem, Ahmed Abd; Twine, Chistopher P; Awad, Wael; Jubouri, Matti; Mohammed, Idhrees; Mestres, Carlos A; Chen, Edward P; Coselli, Joseph S; Williams, Ian M; Bashir, Mohamad (2023). Myths and methodologies: Cardiopulmonary exercise testing for surgical risk stratification in patients with an abdominal aortic aneurysm; balancing risk over benefit. Experimental Physiology, 108(9):1118-1131.

Abstract

The extent to which patients with an abdominal aortic aneurysm (AAA) should exercise remains unclear, given theoretical concerns over the perceived risk of blood pressure‐induced rupture, which is often catastrophic. This is especially pertinent during cardiopulmonary exercise testing, when patients are required to perform incremental exercise to symptom‐limited exhaustion for the determination of cardiorespiratory fitness. This multimodal metric is being used increasingly as a complementary diagnostic tool to inform risk stratification and subsequent management of patients undergoing AAA surgery. In this review, we bring together a multidisciplinary group of physiologists, exercise scientists, anaesthetists, radiologists and surgeons to challenge the enduring ‘myth’ that AAA patients should be fearful of and avoid rigorous exercise. On the contrary, by appraising fundamental vascular mechanobiological forces associated with exercise, in conjunction with ‘methodological’ recommendations for risk mitigation specific to this patient population, we highlight that the benefits conferred by cardiopulmonary exercise testing and exercise training across the continuum of intensity far outweigh the short‐term risks posed by potential AAA rupture.

Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiac Surgery
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Life Sciences > Physiology
Health Sciences > Nutrition and Dietetics
Health Sciences > Physiology (medical)
Uncontrolled Keywords:Physiology, Physiology (medical), Nutrition and Dietetics, Physiology, Physiology (medical), Nutrition and Dietetics
Language:English
Date:1 September 2023
Deposited On:12 Mar 2024 10:55
Last Modified:25 Jun 2025 03:38
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:0958-0670
OA Status:Gold
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1113/ep090816
PubMed ID:37232485
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