Header

UZH-Logo

Maintenance Infos

Particular behavioral symptomatology in patients with rare autosomal chromosome aberrations


Schinzel, Albert (1981). Particular behavioral symptomatology in patients with rare autosomal chromosome aberrations. In: Symposium of the European Society of Human Genetics, Zurich, Switzerland, 26 March 1981 - 28 March 1981. Elsevier, 195-210.

Abstract

It is well known that mental deficiency is the most consistent and most frequent finding in patients with unbalanced autosomal chromosome aberrations. By contrast, very little is known about abnormal behavior in patients with autosomal chromosome aberrations, especialiy in those who do not display a severe degree of mental retardation. The reason for this lack of knowledge is most probably not that these patients never show abnormal behavior, but, as
most cytogenetic case reports focus on cytogenetic findings and secondly on phenotypic anomalies of the patients, it is more likely that very little attention has been drawn so far to behavioral abnormalities. It is striking that most case reports with detailed descriptions of behavior and psychological features originate from Denmark where physicians are apparently more interested in this point than elsewhere.
The following paper will mainly review autosomal chromosome aberrations which mostly do not cause severe or profound mental deficiency and in whom at least a significant proportion of probands display behavioral difficulties. In
addition, the present stage of knowledge on the behavior of patients with autosomal chromosome aberrations whose intelligence is normal will shortly be reviewed.

Abstract

It is well known that mental deficiency is the most consistent and most frequent finding in patients with unbalanced autosomal chromosome aberrations. By contrast, very little is known about abnormal behavior in patients with autosomal chromosome aberrations, especialiy in those who do not display a severe degree of mental retardation. The reason for this lack of knowledge is most probably not that these patients never show abnormal behavior, but, as
most cytogenetic case reports focus on cytogenetic findings and secondly on phenotypic anomalies of the patients, it is more likely that very little attention has been drawn so far to behavioral abnormalities. It is striking that most case reports with detailed descriptions of behavior and psychological features originate from Denmark where physicians are apparently more interested in this point than elsewhere.
The following paper will mainly review autosomal chromosome aberrations which mostly do not cause severe or profound mental deficiency and in whom at least a significant proportion of probands display behavioral difficulties. In
addition, the present stage of knowledge on the behavior of patients with autosomal chromosome aberrations whose intelligence is normal will shortly be reviewed.

Statistics

Altmetrics

Downloads

3 downloads since deposited on 09 Apr 2024
3 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Conference or Workshop Item (Paper), not_refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Medical Genetics
Dewey Decimal Classification:610 Medicine & health
570 Life sciences; biology
Uncontrolled Keywords:Genetics, Genetics (clinical)
Language:English
Event End Date:28 March 1981
Deposited On:09 Apr 2024 06:42
Last Modified:09 Apr 2024 06:42
Publisher:Elsevier
ISBN:9780444803573
OA Status:Green
  • Content: Published Version
  • Language: English