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Impact of aging on maximal oxygen uptake in female runners and sedentary controls

Dos Anjos Souza, Vinícius Ribeiro; Vivan, Lavínia; Seffrin, Aldo; Vallini, Lucca; de Paula Domingos, Fabio; de Lira, Claudio Andre Barbosa; Vancini, Rodrigo Luiz; Weiss, Katja; Rosemann, Thomas; Knechtle, Beat; Andrade, Marilia Santos (2024). Impact of aging on maximal oxygen uptake in female runners and sedentary controls. Experimental Gerontology, 193:112476.

Abstract

The present study aimed to compare V̇O$_{2}$max (absolute, adjusted to total body mass, and adjusted to lean mass) in recreational runners and sedentary women < and > 50 yr and verify the effect of aging and physical activity level on the three types of V̇O$_{2}$ max expression. The study included 147 women:85 runners (45.7 ± 14.1 yr) and 62 sedentary controls (48.8 ± 9.8 yr). They were subjected to cardiopulmonary exercise testing for V̇O$_{2}$ max measurement and a body composition test by dual-emission X-ray absorptiometry system. V̇O$_{2}$max were expressed as absolute values (L/min), relative to total body mass values (mL/kg/min), and relative to lean mass values (mL/kgLM/min). The two-way analysis of variance revealed a significant interaction [F(2,131) = 4.43, p < 0.001] and effects of age group [F(2,131) = 32.79, p < 0.001] and physical activity group [F(2,131) = 55.64, p < 0.001] on V̇O$_{2}$max (mL/min). V̇O$_{2}$max (mL/kg/min) and V̇O$_{2}$ max (mL/kgLM/min) were significantly influenced by age and physical activity levels. The multiple regression model explains 76.2 % of the dependent variable V̇O$_{2}$max (mL/kg/min), age (β = -0.335, t = -7.841, p < 0.001), and physical activity group (β = -0.784, t = -18.351, p < 0.001). In conclusion, female runners had higher V̇O$_{2}$ max values than sedentary women at all ages, even though aging has a greater impact on V̇O$_{2}$ max in the runners group. In addition to cardiorespiratory fitness, women's metabolic lean mass function, as measured by V̇O$_{2}$max adjusted by lean mass, is significantly influenced by aging. Finally, physical activity has a greater impact on V̇O$_{2}$ max levels than aging.

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of General Practice
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Life Sciences > Biochemistry
Life Sciences > Aging
Life Sciences > Molecular Biology
Life Sciences > Genetics
Life Sciences > Endocrinology
Life Sciences > Cell Biology
Uncontrolled Keywords:Body composition; Endurance; Exercise; Physical fitness; Women
Language:English
Date:August 2024
Deposited On:04 Jul 2024 09:01
Last Modified:31 Dec 2024 04:36
Publisher:Elsevier
ISSN:0531-5565
OA Status:Hybrid
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1016/j.exger.2024.112476
PubMed ID:38830478
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  • Language: English
  • Licence: Creative Commons: Attribution 4.0 International (CC BY 4.0)

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