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Müller, Michelle Jessy; Dorst, Andrea; Paulus, Constanze; Khan, Imran; Sieber, Simon (2022). Catch-enrich-release approach for amine-containing natural products. Chemical Communications, 58(90):12560-12563.
Amine-containing natural products are an important class of therapeutic compounds. Herein, we report a chemoselective approach to catch and enrich amine-containing natural products, and release them as underivatized compounds. The strategy exploits the selectivity of the enzyme legumain for the specific release of amine-containing natural products.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 07 Faculty of Science > Department of Chemistry
07 Faculty of Science > Department of Plant and Microbial Biology |
| Dewey Decimal Classification: | 540 Chemistry
580 Plants (Botany) |
| Scopus Subject Areas: | Physical Sciences > Electronic, Optical and Magnetic Materials
Physical Sciences > Catalysis Physical Sciences > Ceramics and Composites Physical Sciences > General Chemistry Physical Sciences > Surfaces, Coatings and Films Physical Sciences > Metals and Alloys Physical Sciences > Materials Chemistry |
| Language: | English |
| Date: | 10 November 2022 |
| Deposited On: | 12 May 2025 07:51 |
| Last Modified: | 29 Jun 2025 01:37 |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 1359-7345 |
| OA Status: | Hybrid |
| Free access at: | Publisher DOI. An embargo period may apply. |
| Publisher DOI: | https://doi.org/10.1039/d2cc04905h |
| PubMed ID: | 36264220 |
| Project Information: |
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Müller, Michelle Jessy