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Machine learning prediction of prime editing efficiency across diverse chromatin contexts

Mathis, Nicolas; Allam, Ahmed; Tálas, András; Kissling, Lucas; Benvenuto, Elena; Schmidheini, Lukas; Schep, Ruben; Damodharan, Tanav; Balazs, Zsolt; Janjuha, Sharan; Ioannidi, Eleonora I; Böck, Desirée; van Steensel, Bas; Krauthammer, Michael; Schwank, Gerald (2025). Machine learning prediction of prime editing efficiency across diverse chromatin contexts. Nature Biotechnology, 43(5):712-719.

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Pharmacology and Toxicology
07 Faculty of Science > Institute of Pharmacology and Toxicology

07 Faculty of Science > Department of Quantitative Biomedicine
Special Collections > Centers of Competence > Competence Centre Language and Medicine Zurich
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Life Sciences > Biotechnology
Physical Sciences > Bioengineering
Life Sciences > Applied Microbiology and Biotechnology
Life Sciences > Molecular Medicine
Physical Sciences > Biomedical Engineering
Language:English
Date:1 May 2025
Deposited On:26 Nov 2024 13:15
Last Modified:30 May 2025 01:40
Publisher:Nature Publishing Group
ISSN:1087-0156
OA Status:Closed
Publisher DOI:https://doi.org/10.1038/s41587-024-02268-2
PubMed ID:38907037
Project Information:
  • Funder: Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
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  • Funder: Federal Department of Economic Affairs, Education and Research, Switzerland | Staatssekretariat für Bildung, Forschung und Innovation
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  • Funder: University Research Priority Program - University of Zurich
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  • Funder: Promedica Stiftung
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  • Funder: Citrin Foundation
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  • Funder: European Molecular Biology Organization
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