Abstract
Guanidino-modified phthalocyanines are evaluated in vitro (polymerase-stop assays and FRET) and in cultured cells as G4-DNA ligands and modulators of gene transcription.
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Membrino, A; Paramasivam, M; Cogoi, S; Alzeer, J; Luedtke, N W; Xodo, L E (2010). Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes. Chemical Communications, 46(4):625-627.
Guanidino-modified phthalocyanines are evaluated in vitro (polymerase-stop assays and FRET) and in cultured cells as G4-DNA ligands and modulators of gene transcription.
Item Type: | Journal Article, refereed, original work |
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Communities & Collections: | 07 Faculty of Science > Department of Chemistry |
Dewey Decimal Classification: | 540 Chemistry |
Scopus Subject Areas: | Physical Sciences > Catalysis
Physical Sciences > Electronic, Optical and Magnetic Materials Physical Sciences > Ceramics and Composites Physical Sciences > General Chemistry Physical Sciences > Surfaces, Coatings and Films Physical Sciences > Metals and Alloys Physical Sciences > Materials Chemistry |
Language: | English |
Date: | 2010 |
Deposited On: | 24 Jan 2010 10:14 |
Last Modified: | 03 May 2025 01:40 |
Publisher: | Royal Society of Chemistry |
ISSN: | 1359-7345 |
Additional Information: | Publikationsdatum der Epub-Version: 2009 Nov 20 |
OA Status: | Green |
Publisher DOI: | https://doi.org/10.1039/b918964e |
PubMed ID: | 20062883 |