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DaedalusData: Exploration, Knowledge Externalization and Labeling of Particles in Medical Manufacturing — A Design Study

Wyss, Alexander; Morgenshtern, Gabriela; Hirsch-Hüsler, Amanda; Bernard, Jürgen (2024). DaedalusData: Exploration, Knowledge Externalization and Labeling of Particles in Medical Manufacturing — A Design Study. IEEE Transactions on Visualization and Computer Graphics, 31(1):54-64.

Abstract

In medical diagnostics of both early disease detection and routine patient care, particle-based contamination of in-vitro diagnostics consumables poses a significant threat to patients. Objective data-driven decision-making on the severity of contamination is key for reducing patient risk, while saving time and cost in quality assessment. Our collaborators introduced us to their quality control process, including particle data acquisition through image recognition, feature extraction, and attributes reflecting the production context of particles. Shortcomings in the current process are limitations in exploring thousands of images, data-driven decision making, and ineffective knowledge externalization. Following the design study methodology, our contributions are a characterization of the problem space and requirements, the development and validation of DaedalusData, a comprehensive discussion of our study's learnings, and a generalizable framework for knowledge externalization. DaedalusData is a visual analytics system that enables domain experts to explore particle contamination patterns, label particles in label alphabets, and externalize knowledge through semi-supervised label-informed data projections. The results of our case study and user study show high usability of DaedalusData and its efficient support of experts in generating comprehensive overviews of thousands of particles, labeling of large quantities of particles, and externalizing knowledge to augment the dataset further. Reflecting on our approach, we discuss insights on dataset augmentation via human knowledge externalization, and on the scalability and trade-offs that come with the adoption of this approach in practice.

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:03 Faculty of Economics > Department of Informatics
08 Research Priority Programs > Digital Society Initiative
Dewey Decimal Classification:000 Computer science, knowledge & systems
Scopus Subject Areas:Physical Sciences > Software
Physical Sciences > Signal Processing
Physical Sciences > Computer Vision and Pattern Recognition
Physical Sciences > Computer Graphics and Computer-Aided Design
Language:English
Date:23 September 2024
Deposited On:06 Dec 2024 10:11
Last Modified:28 Jun 2025 03:33
Publisher:Institute of Electrical and Electronics Engineers
ISSN:1077-2626
OA Status:Green
Publisher DOI:https://doi.org/10.1109/tvcg.2024.3456329
Project Information:
  • Funder: Roche Diagnostics Global Operations Consumables
  • Grant ID:
  • Project Title:
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  • Content: Accepted Version
  • Language: English
  • Licence: Creative Commons: Attribution 4.0 International (CC BY 4.0)

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