Abstract
The 3D structures of all 12 mispairs formed in the active site of a DNA polymerase help explain their differential effects on polymerase stalling and on translocation of the primer terminus to the enzyme's proofreading site.
Jiricny, J (2004). Unfaithful DNA polymerase caught in the act. Molecular Cell, 13(6):768-769.
Abstract
The 3D structures of all 12 mispairs formed in the active site of a DNA polymerase help explain their differential effects on polymerase stalling and on translocation of the primer terminus to the enzyme's proofreading site.
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| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > Institute of Molecular Cancer Research
07 Faculty of Science > Institute of Molecular Cancer Research |
| Dewey Decimal Classification: | 570 Life sciences; biology |
| Language: | English |
| Date: | 2004 |
| Deposited On: | 09 Jul 2010 07:36 |
| Last Modified: | 23 Nov 2018 19:53 |
| Publisher: | Elsevier |
| ISSN: | 1097-2765 |
| OA Status: | Green |
| Free access at: | Publisher DOI. An embargo period may apply. |
| Publisher DOI: | https://doi.org/10.1016/S1097-2765(04)00149-2 |
| PubMed ID: | 15053870 |
Jiricny, J