Abstract
The 3D structures of all 12 mispairs formed in the active site of a DNA polymerase help explain their differential effects on polymerase stalling and on translocation of the primer terminus to the enzyme's proofreading site.
Jiricny, J (2004). Unfaithful DNA polymerase caught in the act. Molecular Cell, 13(6):768-769.
The 3D structures of all 12 mispairs formed in the active site of a DNA polymerase help explain their differential effects on polymerase stalling and on translocation of the primer terminus to the enzyme's proofreading site.
The 3D structures of all 12 mispairs formed in the active site of a DNA polymerase help explain their differential effects on polymerase stalling and on translocation of the primer terminus to the enzyme's proofreading site.
Item Type: | Journal Article, refereed, original work |
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Communities & Collections: | 04 Faculty of Medicine > Institute of Molecular Cancer Research
07 Faculty of Science > Institute of Molecular Cancer Research |
Dewey Decimal Classification: | 570 Life sciences; biology |
Scopus Subject Areas: | Life Sciences > Molecular Biology
Life Sciences > Cell Biology |
Language: | English |
Date: | 2004 |
Deposited On: | 09 Jul 2010 07:36 |
Last Modified: | 23 Jan 2022 16:09 |
Publisher: | Elsevier |
ISSN: | 1097-2765 |
OA Status: | Hybrid |
Free access at: | Publisher DOI. An embargo period may apply. |
Publisher DOI: | https://doi.org/10.1016/S1097-2765(04)00149-2 |
PubMed ID: | 15053870 |
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