Abstract
High-resolution crystal structures of DNA complexes with the bacterial MutM protein show how the enzyme feels its way around the double helix in search of an oxidized guanine before flipping it out into its active site and excising it.
Jiricny, J (2010). DNA repair: how MutM finds the needle in a haystack. Current Biology, 20(4):R145-R147.
High-resolution crystal structures of DNA complexes with the bacterial MutM protein show how the enzyme feels its way around the double helix in search of an oxidized guanine before flipping it out into its active site and excising it.
High-resolution crystal structures of DNA complexes with the bacterial MutM protein show how the enzyme feels its way around the double helix in search of an oxidized guanine before flipping it out into its active site and excising it.
Item Type: | Journal Article, refereed, original work |
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Communities & Collections: | 04 Faculty of Medicine > Institute of Molecular Cancer Research
07 Faculty of Science > Institute of Molecular Cancer Research |
Dewey Decimal Classification: | 570 Life sciences; biology |
Scopus Subject Areas: | Life Sciences > General Biochemistry, Genetics and Molecular Biology
Life Sciences > General Agricultural and Biological Sciences |
Language: | English |
Date: | 23 February 2010 |
Deposited On: | 17 May 2010 21:30 |
Last Modified: | 23 Jan 2022 16:48 |
Publisher: | Elsevier |
ISSN: | 0960-9822 |
OA Status: | Closed |
Publisher DOI: | https://doi.org/10.1016/j.cub.2009.12.046 |
PubMed ID: | 20178755 |
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