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DNA repair: how MutM finds the needle in a haystack


Jiricny, J (2010). DNA repair: how MutM finds the needle in a haystack. Current Biology, 20(4):R145-R147.

Abstract

High-resolution crystal structures of DNA complexes with the bacterial MutM protein show how the enzyme feels its way around the double helix in search of an oxidized guanine before flipping it out into its active site and excising it.

Abstract

High-resolution crystal structures of DNA complexes with the bacterial MutM protein show how the enzyme feels its way around the double helix in search of an oxidized guanine before flipping it out into its active site and excising it.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Molecular Cancer Research
07 Faculty of Science > Institute of Molecular Cancer Research
Dewey Decimal Classification:570 Life sciences; biology
Language:English
Date:23 February 2010
Deposited On:17 May 2010 21:30
Last Modified:17 Feb 2018 17:03
Publisher:Elsevier
ISSN:0960-9822
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.cub.2009.12.046
PubMed ID:20178755

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