Mlostoń, Grzegorz; Obijalska, E; Heimgartner, H (2010). Synthesis of β-amino-α-trifluoromethyl alcohols and their applications in organic synthesis. Journal of Fluorine Chemistry, 131(8):829-843.
A comprehensive overview on methods applied for syntheses of β-amino-α-trifluoromethyl alcohols, including stereocontrolled variants, is presented. In addition, reported cases of the exploration of β-amino-α-trifluoromethyl alcohols for the preparation of trifluoromethylated peptidomimetics and other biologically active, fluorinated compounds are discussed. Attractive opportunities for their applications as organocatalysts are also presented.
A comprehensive overview on methods applied for syntheses of β-amino-α-trifluoromethyl alcohols, including stereocontrolled variants, is presented. In addition, reported cases of the exploration of β-amino-α-trifluoromethyl alcohols for the preparation of trifluoromethylated peptidomimetics and other biologically active, fluorinated compounds are discussed. Attractive opportunities for their applications as organocatalysts are also presented.
| Item Type: | Journal Article, refereed, further contribution |
|---|---|
| Communities & Collections: | 07 Faculty of Science > Department of Chemistry |
| Dewey Decimal Classification: | 540 Chemistry |
| Scopus Subject Areas: | Life Sciences > Biochemistry
Physical Sciences > Environmental Chemistry Physical Sciences > Physical and Theoretical Chemistry Physical Sciences > Organic Chemistry Physical Sciences > Inorganic Chemistry |
| Language: | English |
| Date: | August 2010 |
| Deposited On: | 15 Jul 2010 15:18 |
| Last Modified: | 05 Dec 2023 02:40 |
| Publisher: | Elsevier |
| ISSN: | 0022-1139 |
| Funders: | Polish Ministry for Science and Higher Education, F. Hoffmann-La Roche AG, Basel |
| OA Status: | Hybrid |
| Publisher DOI: | https://doi.org/10.1016/j.jfluchem.2010.05.014 |
Mlostoń, Grzegorz