Navigation auf zora.uzh.ch

Search ZORA

ZORA (Zurich Open Repository and Archive)

Peptidomimetic inhibitors targeting the CCR5-binding site on the human immunodeficiency virus Type-1 gp120 glycoprotein complexed to CD4

Seitz, M; Rusert, P; Moehle, K; Trkola, A; Robinson, J A (2010). Peptidomimetic inhibitors targeting the CCR5-binding site on the human immunodeficiency virus Type-1 gp120 glycoprotein complexed to CD4. Chemical Communications, 46(41):7754-7756.

Abstract

A helical tyrosine-sulfated epitope in CCR5 that is recognized by the human immunodeficiency virus type-1 envelope glycoprotein gp120 in its CD4-induced conformation can be mimicked structurally by a cyclic ß-hairpin peptide containing two sulfated tyrosine residues at positons i and i+2 along one ß-strand.

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Department of Chemistry
Dewey Decimal Classification:540 Chemistry
Scopus Subject Areas:Physical Sciences > Catalysis
Physical Sciences > Electronic, Optical and Magnetic Materials
Physical Sciences > Ceramics and Composites
Physical Sciences > General Chemistry
Physical Sciences > Surfaces, Coatings and Films
Physical Sciences > Metals and Alloys
Physical Sciences > Materials Chemistry
Language:English
Date:2010
Deposited On:24 Jan 2011 14:49
Last Modified:05 Mar 2025 02:36
Publisher:Royal Society of Chemistry
ISSN:1359-7345
Funders:SNF
OA Status:Green
Publisher DOI:https://doi.org/10.1039/C0CC02913K
PubMed ID:20830376
Project Information:
  • Funder: SNSF
  • Grant ID:
  • Project Title: SNF
Download PDF  'Peptidomimetic inhibitors targeting the CCR5-binding site on the human immunodeficiency virus Type-1 gp120 glycoprotein complexed to CD4'.
Preview
  • Content: Accepted Version

Metadata Export

Statistics

Citations

Dimensions.ai Metrics
9 citations in Web of Science®
11 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

162 downloads since deposited on 24 Jan 2011
17 downloads since 12 months
Detailed statistics

Authors, Affiliations, Collaborations

Similar Publications