Spike-based learning circuits have been typically used in conjunction with linear integrate-and-fire neurons. As a new class of current-mode conductance-based silicon neurons has been recently developed, it is important to evaluate how the spike-based learning circuits perform, when interfaced to these new types of neuron circuits. Here, we describe a VLSI implementation of a current-mode conductance-based neuron, connected to synaptic circuits with spike-based learning capabilities. The conductance-based silicon neuron has built-in spike-frequency adaptation, refractory period mechanisms, and plasticity eligibility control circuits. The synaptic circuits exhibits realistic dynamics in the post-synaptic currents and comprise local spike-based learning circuits, controlled by the global post-synaptic eligibility circuits. We present experimental results which characterize the conductance-based neuron circuit properties and the spike-based learning circuits connected to it.