Rozenberg, I; Sluka, S H M; Rohrer, L; Hofmann, J; Becher, B; Akhmedov, A; Soliz, J; Mocharla, P; Borén, J; Johansen, P; Steffel, J; Watanabe, T; Lüscher, T F; Tanner, F C (2010). Histamine H1 receptor promotes atherosclerotic lesion formation by increasing vascular permeability for low-density lipoproteins. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(5):923-930.
These data indicate that H1 but not H2 receptor activation drives the formation of atherosclerotic lesions through an increased vascular permeability for LDL, which is associated with an enhanced secondary aortic and systemic inflammation. These data open novel perspectives for the prevention and treatment of atherosclerotic vascular disease.
These data indicate that H1 but not H2 receptor activation drives the formation of atherosclerotic lesions through an increased vascular permeability for LDL, which is associated with an enhanced secondary aortic and systemic inflammation. These data open novel perspectives for the prevention and treatment of atherosclerotic vascular disease.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > University Hospital Zurich > Institute of Clinical Chemistry
04 Faculty of Medicine > University Hospital Zurich > Dermatology Clinic 04 Faculty of Medicine > Institute of Experimental Immunology |
| Dewey Decimal Classification: | 570 Life sciences; biology
610 Medicine & health 540 Chemistry |
| Language: | English |
| Date: | 2010 |
| Deposited On: | 06 Jan 2011 15:08 |
| Last Modified: | 17 Feb 2018 17:56 |
| Publisher: | Lippincott Wiliams & Wilkins |
| ISSN: | 1079-5642 |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1161/ATVBAHA.109.201079 |
| PubMed ID: | 20203300 |
Rozenberg, I