Eisele, Y S; Obermüller, U; Heilbronner, G; Baumann, F; Kaeser, S A; Wolburg, H; Walker, L C; Staufenbiel, M; Heikenwalder, M; Jucker, M (2010). Peripherally applied Aβ-containing inoculates induce cerebral β-amyloidosis. Science, 330(6006):980-982.
The intracerebral injection of β-amyloid-containing brain extracts can induce cerebral β-amyloidosis and associated pathologies in susceptible hosts. We found that intraperitoneal inoculation with β-amyloid-rich extracts induced β-amyloidosis in the brains of β-amyloid precursor protein transgenic mice after prolonged incubation times.
The intracerebral injection of β-amyloid-containing brain extracts can induce cerebral β-amyloidosis and associated pathologies in susceptible hosts. We found that intraperitoneal inoculation with β-amyloid-rich extracts induced β-amyloidosis in the brains of β-amyloid precursor protein transgenic mice after prolonged incubation times.
| Other titles: | Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis |
|---|---|
| Item Type: | Journal Article, refereed, original work |
| Communities & Collections: | 04 Faculty of Medicine > University Hospital Zurich > Institute of Neuropathology |
| Dewey Decimal Classification: | 570 Life sciences; biology
610 Medicine & health |
| Scopus Subject Areas: | Health Sciences > Multidisciplinary |
| Language: | English |
| Date: | 2010 |
| Deposited On: | 19 Jan 2011 13:50 |
| Last Modified: | 28 Jun 2022 13:22 |
| Publisher: | American Association for the Advancement of Science (AAAS) |
| ISSN: | 0036-8075 |
| Additional Information: | Comment in: Science. 2010 Nov 12;330(6006):918-9. |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1126/science.1194516 |
| PubMed ID: | 20966215 |
Eisele, Y S