In the title molecule, C26H28N2O3, the piperidine ring adopts a chair conformation. The two methoxyphenyl groups attached to the piperidine ring at positions 2 and 6 have equatorial orientations, and make a dihedral angle of 80.72 (15) deg. The benzyl group at position 3 has an equatorial orientation. The oxime group at position 4 has a bisectional orientation. The ring of the benzyl group makes dihedral angles of 64.71 (16) and 84.79 (17) deg. with the two benzene rings. Molecules are linked by intermolecular N-H...O, O-H...N and C-H...O hydrogen bonds, and C—H...pi interactions. There is also a C-H...O intramolecular interaction.