Abstract
Our results suggest that apoptosing INS-1 cells shed microparticles that may stimulate PSP/reg induction in neighboring cells, a mechanism that may facilitate the recovery of β-cell mass in HNF1A-MODY.
Bonner, C; Bacon, S; Concannon, C G; Rizvi, S R; Baquié, M; Farrelly, A M; Kilbride, S M; Dussmann, H; Ward, M W; Boulanger, C M; Wollheim, C B; Graf, R; Byrne, M M; Prehn, J H M (2010). INS-1 cells undergoing caspase-dependent apoptosis enhance the regenerative capacity of neighboring cells. Diabetes, 59(11):2799-2808.
Our results suggest that apoptosing INS-1 cells shed microparticles that may stimulate PSP/reg induction in neighboring cells, a mechanism that may facilitate the recovery of β-cell mass in HNF1A-MODY.
Our results suggest that apoptosing INS-1 cells shed microparticles that may stimulate PSP/reg induction in neighboring cells, a mechanism that may facilitate the recovery of β-cell mass in HNF1A-MODY.
Item Type: | Journal Article, refereed, original work |
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Communities & Collections: | 04 Faculty of Medicine > University Hospital Zurich > Clinic for Visceral and Transplantation Surgery |
Dewey Decimal Classification: | 610 Medicine & health |
Scopus Subject Areas: | Health Sciences > Internal Medicine
Health Sciences > Endocrinology, Diabetes and Metabolism |
Language: | English |
Date: | 2010 |
Deposited On: | 14 Apr 2011 09:28 |
Last Modified: | 23 Jan 2022 18:32 |
Publisher: | American Diabetes Association |
ISSN: | 0012-1797 |
Additional Information: | The accepted manuscript is an author-created, uncopyedited electronic version of an article accepted for publication in Diabetes (http://diabetes.diabetesjournals.org). The American Diabetes Association (ADA), publisher of Diabetes, is not responsible for any errors or omissions in this version of the manuscript or any version derived from it by third parties. The definitive publisher-authenticated version is available online at DOI 10.2337/db09-1478. |
OA Status: | Hybrid |
Free access at: | PubMed ID. An embargo period may apply. |
Publisher DOI: | https://doi.org/10.2337/db09-1478 |
PubMed ID: | 20682686 |
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