Pörksen, S; Laborie, L B; et al; Schönle, E J (2010). Disease progression and search for monogenic diabetes among children with new onset type 1 diabetes negative for ICA, GAD- and IA-2 Antibodies. BMC endocrine disorders, (10):16.
GAD, IA-2A, and ICA negative children with new onset type 1 diabetes have slower disease progression as assessed by residual beta-cell function and improved glycemic control 12 months after diagnosis. One out of 24 had a mutation in ABCC8, suggesting that screening of ABCC8 should be considered in patients with AAB negative type 1 diabetes.
GAD, IA-2A, and ICA negative children with new onset type 1 diabetes have slower disease progression as assessed by residual beta-cell function and improved glycemic control 12 months after diagnosis. One out of 24 had a mutation in ABCC8, suggesting that screening of ABCC8 should be considered in patients with AAB negative type 1 diabetes.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic |
| Dewey Decimal Classification: | 610 Medicine & health |
| Scopus Subject Areas: | Health Sciences > Endocrinology, Diabetes and Metabolism |
| Language: | English |
| Date: | 2010 |
| Deposited On: | 21 Feb 2011 16:17 |
| Last Modified: | 23 Jan 2022 18:34 |
| Publisher: | UNSPECIFIED |
| ISSN: | 1472-6823 |
| OA Status: | Gold |
| Free access at: | PubMed ID. An embargo period may apply. |
| Publisher DOI: | https://doi.org/10.1186/1472-6823-10-16 |
| Related URLs: | http://www.biomedcentral.com/1472-6823/10/16 (Publisher) |
| PubMed ID: | 20863361 |
Pörksen, S