Syntheses, structural characterization and CO releasing properties of boranocarbonate H3BCO2H](-) derivatives

Abstract

CO plays an important role in biological processes and molecules which release CO in a controllable way could therefore be used for medicinal purposes. Beside organometallic carbonyl complexes, boranocarbonate H3BCO2H](-) is one of the most promising candidates but releases CO too rapidly. In order to delay the CO release, we have prepared boranocarbamates H3BCONH-R] from H3BCO2H] which comprise histamine, morpholine, aniline and ethylene-diamine bound via amides to the {H3BCO} moiety. The syntheses of the new derivatives is described together with their structural characterization. These compounds release CO at a much slower rate than the parent compound and are therefore potential CO releasing molecules for biological and medicinal application.