Abstract
The transporter specificity of (99m)Tc-mebrofenin and ICG partially overlaps as both compounds are transported by OATP1B3. (99m)Tc-mebrofenin is also taken up by OATP1B1, whereas ICG is additionally transported by NTCP.
de Graaf, W; Häusler, S; Heger, M; van Ginhoven, T M; van Cappellen, G; Bennink, R J; Kullak-Ublick, G A; Hesselmann, R; van Gulik, T M; Stieger, B (2011). Transporters involved in the hepatic uptake of (99m)Tc-mebrofenin and indocyanine green. Journal of Hepatology, 54(4):738-745.
The transporter specificity of (99m)Tc-mebrofenin and ICG partially overlaps as both compounds are transported by OATP1B3. (99m)Tc-mebrofenin is also taken up by OATP1B1, whereas ICG is additionally transported by NTCP.
The transporter specificity of (99m)Tc-mebrofenin and ICG partially overlaps as both compounds are transported by OATP1B3. (99m)Tc-mebrofenin is also taken up by OATP1B1, whereas ICG is additionally transported by NTCP.
Item Type: | Journal Article, refereed, original work |
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Communities & Collections: | 04 Faculty of Medicine > University Hospital Zurich > Clinic for Clinical Pharmacology and Toxicology |
Dewey Decimal Classification: | 610 Medicine & health |
Scopus Subject Areas: | Health Sciences > Hepatology |
Language: | English |
Date: | 2011 |
Deposited On: | 23 Aug 2011 14:18 |
Last Modified: | 01 Jul 2022 14:34 |
Publisher: | Elsevier |
ISSN: | 0168-8278 |
OA Status: | Green |
Publisher DOI: | https://doi.org/10.1016/j.jhep.2010.07.047 |
PubMed ID: | 21163547 |
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