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Memory-related hippocampal dysfunction in poly-drug ecstasy (3,4-methylenedioxymethamphetamine) users


Daumann, J; Fischermann, T; Heekeren, K; Henke, K; Thron, A; Gouzoulis-Mayfrank, E (2005). Memory-related hippocampal dysfunction in poly-drug ecstasy (3,4-methylenedioxymethamphetamine) users. Psychopharmacology, 180(4):607-611.

Abstract

These results provide evidence for abnormal hippocampal functioning in MDMA users even at the presence of normal memory performance. This finding may be linked to MDMA-induced neurotoxicity and suggests that diminished hippocampal activation during memory retrieval might be a more sensitive or earlier index of MDMA-related neurotoxicity than neuropsychological performance.

Abstract

These results provide evidence for abnormal hippocampal functioning in MDMA users even at the presence of normal memory performance. This finding may be linked to MDMA-induced neurotoxicity and suggests that diminished hippocampal activation during memory retrieval might be a more sensitive or earlier index of MDMA-related neurotoxicity than neuropsychological performance.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute for Regenerative Medicine (IREM)
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Life Sciences > Pharmacology
Uncontrolled Keywords:Pharmacology
Language:English
Date:2005
Deposited On:02 Sep 2011 11:09
Last Modified:23 Jan 2022 19:07
Publisher:Springer
ISSN:0033-3158
OA Status:Closed
Publisher DOI:https://doi.org/10.1007/s00213-004-2002-8
PubMed ID:15372137
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