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A chimeric GPCR model mimicking the ligand binding site of the human Y1 receptor studied by NMR spectroscopy


Walser, R; Kleinschmidt, J H; Zerbe, O (2011). A chimeric GPCR model mimicking the ligand binding site of the human Y1 receptor studied by NMR spectroscopy. ChemBioChem, 12(11):1690-1693.

Abstract

This paper describes the development of a structural mimetic for the extracellular loops of a human GPCR. The three extracellular loops were grafted onto the scaffold of the E.coli outer membrane beta-barrel protein OmpA

Abstract

This paper describes the development of a structural mimetic for the extracellular loops of a human GPCR. The three extracellular loops were grafted onto the scaffold of the E.coli outer membrane beta-barrel protein OmpA

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Department of Chemistry
Dewey Decimal Classification:540 Chemistry
Uncontrolled Keywords:mimetic, , GPCR, , NMR, , structural biology
Language:English
Date:2011
Deposited On:27 Oct 2011 14:24
Last Modified:17 Feb 2018 13:45
Publisher:Wiley-Blackwell
ISSN:1439-4227
OA Status:Closed
Publisher DOI:https://doi.org/10.1002/cbic.201100244
PubMed ID:21695755

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