Brühl, Annette Beatrix; Jäncke, Lutz; Herwig, Uwe (2011). Differential modulation of emotion processing brain regions by noradrenergic and serotonergic antidepressants. Psychopharmacology, 216(3):389-399.
The brain regions involved in the processing of negative emotional stimuli were differentially modulated by selective noradrenergic and serotonergic drugs: thalamic activity was increased by reboxetine, whereas citalopram primarily affected ventrolateral prefrontal regions. Thus, dysfunction in these regions, which could be identified in depressed patients, may predict treatment responses to either noradrenergic or serotonergic antidepressants.
The brain regions involved in the processing of negative emotional stimuli were differentially modulated by selective noradrenergic and serotonergic drugs: thalamic activity was increased by reboxetine, whereas citalopram primarily affected ventrolateral prefrontal regions. Thus, dysfunction in these regions, which could be identified in depressed patients, may predict treatment responses to either noradrenergic or serotonergic antidepressants.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > Psychiatric University Hospital Zurich > Clinic for Clinical and Social Psychiatry Zurich West (former)
06 Faculty of Arts > Institute of Psychology |
| Dewey Decimal Classification: | 150 Psychology
610 Medicine & health |
| Scopus Subject Areas: | Life Sciences > Pharmacology |
| Language: | English |
| Date: | 2011 |
| Deposited On: | 26 Oct 2011 10:15 |
| Last Modified: | 23 Jan 2022 19:23 |
| Publisher: | Springer |
| ISSN: | 0033-3158 |
| OA Status: | Green |
| Publisher DOI: | https://doi.org/10.1007/s00213-011-2227-2 |
| PubMed ID: | 21359508 |
Brühl, Annette Beatrix