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Schittenhelm, J; Simon, P; Harter, P N; Zachskorn, C; Schlaszus, H; Röttger, F; Winkels, M; Weller, M; Meyermann, R; Mittelbronn, M (2011). CD133 expression is associated with small round blue cell tumour morphology in human central nervous system neoplasms. Histopathology, 58(5):739-749.
CD133 expression in human CNS neoplasms is independent of the grade of malignancy but strongly correlates with SRBCT morphology. Together with recent findings showing that CD133 is quickly upregulated upon hypoxia and that CD133(-) cells can also exhibit stem cell properties, our data strongly question the suitability of CD133 as a brain tumour stem cell marker in vivo.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > University Hospital Zurich > Clinic for Neurology |
| Dewey Decimal Classification: | 610 Medicine & health |
| Scopus Subject Areas: | Health Sciences > Pathology and Forensic Medicine
Health Sciences > Histology |
| Language: | English |
| Date: | 2011 |
| Deposited On: | 04 Nov 2011 08:24 |
| Last Modified: | 06 Mar 2025 02:36 |
| Publisher: | Wiley-Blackwell |
| ISSN: | 0309-0167 |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1111/j.1365-2559.2011.03801.x |
| PubMed ID: | 21438906 |
Schittenhelm, J