Header

UZH-Logo

Maintenance Infos

Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography


Götzinger, E; Pircher, M; Geitzenauer, W; Ahlers, C; Baumann, B; Michels, S; Schmidt-Erfurth, U; Hitzenberger, C K (2008). Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography. Optics Express, 16(21):16410-16422.

Abstract

We present a new method for identifying and segmenting the
retinal pigment epithelium (RPE) in polarization sensitive optical coherence tomography (PS-OCT) images of the human retina. Contrary to previous, intensity based segmentation algorithms, our method uses an intrinsic tissue property of the RPE: its depolarizing, or polarization scrambling effect on backscattered light. Two different segmentation algorithms are presented and discussed: a simpler algorithm based on retardation data, and a more sophisticated algorithm based on local variations of the polarization state calculated from averaged Stokes vector elements. By using a state of the art spectral domain PS-OCT instrument, we demonstrate the method in healthy and diseased eyes.

Abstract

We present a new method for identifying and segmenting the
retinal pigment epithelium (RPE) in polarization sensitive optical coherence tomography (PS-OCT) images of the human retina. Contrary to previous, intensity based segmentation algorithms, our method uses an intrinsic tissue property of the RPE: its depolarizing, or polarization scrambling effect on backscattered light. Two different segmentation algorithms are presented and discussed: a simpler algorithm based on retardation data, and a more sophisticated algorithm based on local variations of the polarization state calculated from averaged Stokes vector elements. By using a state of the art spectral domain PS-OCT instrument, we demonstrate the method in healthy and diseased eyes.

Statistics

Citations

Dimensions.ai Metrics
221 citations in Web of Science®
251 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

15 downloads since deposited on 03 Dec 2008
9 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Ophthalmology Clinic
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Physical Sciences > Atomic and Molecular Physics, and Optics
Language:English
Date:2008
Deposited On:03 Dec 2008 13:23
Last Modified:01 Dec 2023 02:46
Publisher:Optical Society of America (OSA)
ISSN:1094-4087
OA Status:Gold
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1364/OE.16.016410
PubMed ID:18852747
  • Content: Published Version
  • Licence: Creative Commons: Attribution 4.0 International (CC BY 4.0)