Wagner, P L; Stiedl, A C; Wilbertz, T; Petersen, K; Scheble, V; Menon, R; Reischl, M; Mikut, R; Rubin, M A; Fend, F; Moch, H; Soltermann, A; Weder, W; Altorki, N K; Perner, S (2011). Frequency and clinicopathologic correlates of KRAS amplification in non-small cell lung carcinoma. Lung Cancer, 74(1):118-123.
KRAS amplification is a common molecular alteration in NSCLC, characterizing ∼15% of tumors. This alteration is associated with indicators of local aggressiveness, and may act synergistically with KRAS mutations to promote tumor progression.
KRAS amplification is a common molecular alteration in NSCLC, characterizing ∼15% of tumors. This alteration is associated with indicators of local aggressiveness, and may act synergistically with KRAS mutations to promote tumor progression.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > University Hospital Zurich > Institute of Pathology and Molecular Pathology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Thoracic Surgery |
| Dewey Decimal Classification: | 610 Medicine & health |
| Scopus Subject Areas: | Health Sciences > Oncology
Health Sciences > Pulmonary and Respiratory Medicine Life Sciences > Cancer Research |
| Language: | English |
| Date: | 2011 |
| Deposited On: | 04 Jan 2012 10:25 |
| Last Modified: | 06 Nov 2023 02:41 |
| Publisher: | Elsevier |
| ISSN: | 0169-5002 |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1016/j.lungcan.2011.01.029 |
| PubMed ID: | 21477882 |
Wagner, P L