Köhler, Sibylle; Tschopp, Oliver; Jacky, Emanuel; Schmid, Christoph (2011). Paraneoplastic hyperthyroidism. BMJ Case Reports, 2011:bcr0420114163.
The authors describe a 31-year-old male with a metastatic germ cell tumour and massively elevated human chorionic gonadotrophin (HCG) levels who presented with hyperthyroidism. As HCG is structurally closely related to thyroid stimulating hormone (TSH), it can activate the TSH receptor; grossly elevated levels may result in hyperthyroidism. After initiation of chemotherapy, HCG levels decreased and hyperthyroidism resolved.
The authors describe a 31-year-old male with a metastatic germ cell tumour and massively elevated human chorionic gonadotrophin (HCG) levels who presented with hyperthyroidism. As HCG is structurally closely related to thyroid stimulating hormone (TSH), it can activate the TSH receptor; grossly elevated levels may result in hyperthyroidism. After initiation of chemotherapy, HCG levels decreased and hyperthyroidism resolved.
| Item Type: | Journal Article, refereed, further contribution |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > University Hospital Zurich > Clinic for Endocrinology and Diabetology |
| Dewey Decimal Classification: | 610 Medicine & health |
| Scopus Subject Areas: | Health Sciences > General Medicine |
| Language: | English |
| Date: | 2011 |
| Deposited On: | 24 Jan 2012 14:39 |
| Last Modified: | 20 Oct 2023 07:18 |
| Publisher: | BMJ Publishing Group |
| ISSN: | 1757-790X |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1136/bcr.04.2011.4163 |
| PubMed ID: | 22688478 |
Köhler, Sibylle