Schwank, G; Yang, S F; Restrepo, S; Basler, K (2012). Comment on "Dynamics of dpp signaling and proliferation control". Science, 335(6067):401.
Wartlick et al. (Research Articles, 4 March 2011, p. 1154) reported that growth rates in the Drosophila wing disc correlate with increasing Dpp signaling levels, suggesting that the rate of Dpp increase determines the cell-cycle length. Contradicting their model, we found that cells in which the increase of Dpp signaling levels was genetically abrogated grew at rates comparable to those of wild-type cells.
Wartlick et al. (Research Articles, 4 March 2011, p. 1154) reported that growth rates in the Drosophila wing disc correlate with increasing Dpp signaling levels, suggesting that the rate of Dpp increase determines the cell-cycle length. Contradicting their model, we found that cells in which the increase of Dpp signaling levels was genetically abrogated grew at rates comparable to those of wild-type cells.
| Item Type: | Journal Article, refereed, further contribution |
|---|---|
| Communities & Collections: | 07 Faculty of Science > Institute of Molecular Life Sciences
Special Collections > SystemsX.ch Special Collections > SystemsX.ch > Research, Technology and Development Projects > WingX |
| Dewey Decimal Classification: | 570 Life sciences; biology |
| Scopus Subject Areas: | Health Sciences > Multidisciplinary |
| Language: | English |
| Date: | 27 January 2012 |
| Deposited On: | 02 Apr 2012 09:10 |
| Last Modified: | 11 Aug 2020 08:23 |
| Publisher: | American Association for the Advancement of Science (AAAS) |
| ISSN: | 0036-8075 |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1126/science.1210997 |
| PubMed ID: | 22282789 |
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Schwank, G