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Yang, X; Fox, T; Berke, H (2011). Ammonia borane as a metal free reductant for ketones and aldehydes: a mechanistic study. Tetrahedron, 67(37):7121-7127.
Without a catalyst ketones and aldehydes were reacted in THF with ammonia borane (AB) to proceed hydroboration forming alkyl borates. Mechanistic studies revealed that dissociation of ammonia from AB occurred before the hydroboration step. When methanol was used as the solvent, metal free methanolysis of AB would take place with the ketone/aldehyde being directly hydrogenated by the MeOH center dot BH(3) complex. (C) 2011 Elsevier Ltd. All rights reserved.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 07 Faculty of Science > Department of Chemistry |
| Dewey Decimal Classification: | 540 Chemistry |
| Scopus Subject Areas: | Life Sciences > Biochemistry
Life Sciences > Drug Discovery Physical Sciences > Organic Chemistry |
| Language: | English |
| Date: | September 2011 |
| Deposited On: | 05 Mar 2012 15:57 |
| Last Modified: | 07 Mar 2025 02:38 |
| Publisher: | Elsevier |
| ISSN: | 0040-4020 |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1016/j.tet.2011.06.104 |
| Other Identification Number: | ISI:000294574400016 |
Yang, X