Nair, Sean P; Bischoff, Markus; Senn, Maria M; Berger-Bächi, Brigitte (2003). The sigma B regulon influences internalization of Staphylococcus aureus by osteoblasts. Infection and Immunity, 71(7):4167-4170.
Individual strains of Staphylococcus aureus have different capacities to become internalized by osteoblasts. Here we report that the levels of sigma(B) expressed by S. aureus correlate with the capacity of this bacterium to be internalized by osteoblasts. However, sigma(B) is not essential for internalization and does not necessarily account for the differences in the capacities of strains to be internalized.
Individual strains of Staphylococcus aureus have different capacities to become internalized by osteoblasts. Here we report that the levels of sigma(B) expressed by S. aureus correlate with the capacity of this bacterium to be internalized by osteoblasts. However, sigma(B) is not essential for internalization and does not necessarily account for the differences in the capacities of strains to be internalized.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > Institute of Medical Microbiology |
| Dewey Decimal Classification: | 570 Life sciences; biology
610 Medicine & health |
| Scopus Subject Areas: | Life Sciences > Parasitology
Life Sciences > Microbiology Life Sciences > Immunology Health Sciences > Infectious Diseases |
| Language: | English |
| Date: | 2003 |
| Deposited On: | 20 Jul 2012 19:50 |
| Last Modified: | 30 Jul 2020 04:56 |
| Publisher: | American Society for Microbiology |
| ISSN: | 0019-9567 |
| OA Status: | Green |
| Free access at: | PubMed ID. An embargo period may apply. |
| Publisher DOI: | https://doi.org/10.1128/IAI.71.7.4167–4170.2003 |
| PubMed ID: | 12819110 |
Nair, Sean P