Header

UZH-Logo

Maintenance Infos

Nonsteroidal antiinflammatory drugs, acetaminophen, and hypertension


Sudano, I; Flammer, A J; Roas, S; Enseleit, F; Noll, G; Ruschitzka, F (2012). Nonsteroidal antiinflammatory drugs, acetaminophen, and hypertension. Current Hypertension Reports, 14(4):304-309.

Abstract

Selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) as well as acetaminophen belong to the most widely prescribed therapeutic agents worldwide. Their efficacy in pain relief notwithstanding, the use of NSAIDs is associated with an increased cardiovascular risk, which can be partly attributed to their blood pressure raising potential. Adequately powered placebo-controlled trials specifically evaluating the cardiovascular safety of NSAIDs vs. selective COX inhibitors are currently underway. This review summarizes the current knowledge on the cardiovascular effects of NSAIDs and acetaminophen, and their potential clinical consequences.

Abstract

Selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) as well as acetaminophen belong to the most widely prescribed therapeutic agents worldwide. Their efficacy in pain relief notwithstanding, the use of NSAIDs is associated with an increased cardiovascular risk, which can be partly attributed to their blood pressure raising potential. Adequately powered placebo-controlled trials specifically evaluating the cardiovascular safety of NSAIDs vs. selective COX inhibitors are currently underway. This review summarizes the current knowledge on the cardiovascular effects of NSAIDs and acetaminophen, and their potential clinical consequences.

Statistics

Citations

Dimensions.ai Metrics
21 citations in Web of Science®
23 citations in Scopus®
19 citations in Microsoft Academic
Google Scholar™

Altmetrics

Downloads

305 downloads since deposited on 31 Jul 2012
54 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2012
Deposited On:31 Jul 2012 15:12
Last Modified:24 Sep 2018 07:20
Publisher:Springer
ISSN:1522-6417
Additional Information:The original publication is available at www.springerlink.com
OA Status:Green
Publisher DOI:https://doi.org/10.1007/s11906-012-0274-7
PubMed ID:22610476

Download

Download PDF  'Nonsteroidal antiinflammatory drugs, acetaminophen, and hypertension'.
Preview
Content: Accepted Version
Filetype: PDF
Size: 185kB
View at publisher