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Environmental factors and their impact on the intestinal microbiota: a role for human disease?


Biedermann, Luc; Rogler, Gerhard (2012). Environmental factors and their impact on the intestinal microbiota: a role for human disease? Digestive Diseases, 30(Suppl. 3):20-27.

Abstract

The intestinal microbiota and its potential role in human health and disease have come into the focus of interest in recent years. An important prerequisite for the achieved advances with regard to a better characterization of its complex composition and influencing factors is the increasing availability and affordability of culture-independent methods, such as high-throughput sequencing technologies. We discuss some general aspects of the intestinal microbiota. Recent insights into its potential pathogenetic role in the metabolic syndrome and inflammatory bowel disease will also be discussed that imply an impact of smoking status and smoking cessation on intestinal microbial composition.

Abstract

The intestinal microbiota and its potential role in human health and disease have come into the focus of interest in recent years. An important prerequisite for the achieved advances with regard to a better characterization of its complex composition and influencing factors is the increasing availability and affordability of culture-independent methods, such as high-throughput sequencing technologies. We discuss some general aspects of the intestinal microbiota. Recent insights into its potential pathogenetic role in the metabolic syndrome and inflammatory bowel disease will also be discussed that imply an impact of smoking status and smoking cessation on intestinal microbial composition.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Gastroenterology and Hepatology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2012
Deposited On:13 Mar 2013 13:30
Last Modified:17 Feb 2018 01:40
Publisher:Karger
ISSN:0257-2753
Additional Information:© 2012 S. Karger AG
OA Status:Green
Publisher DOI:https://doi.org/10.1159/000342590
PubMed ID:23295688

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