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Successful salvage chemotherapy with FOLFIRINOX for recurrent mixed acinar cell carcinoma and ductal adenocarcinoma of the pancreas in an adolescent patient


Pfrommer, Sarah; Weber, Achim; Dutkowski, Philipp; Schäfer, Niklaus G; Müllhaupt, Beat; Bourquin, Jean-Pierre; Breitenstein, Stefan; Pestalozzi, Bernhard C; Stenner, Frank; Renner, Christoph; D'Addario, Giannicola; Graf, Hans-Jörg; Knuth, Alexander; Clavien, Pierre-Alain; Samaras, Panagiotis (2013). Successful salvage chemotherapy with FOLFIRINOX for recurrent mixed acinar cell carcinoma and ductal adenocarcinoma of the pancreas in an adolescent patient. Case Reports in Oncology, 6(3):497-503.

Abstract

Pancreatic tumors are rare in children and adolescents. Here, we report the case of a 15-year-old boy who presented with a mixed acinar cell carcinoma/ductal adenocarcinoma with blastomatous components. He received multimodal treatment including various chemotherapy regimens and multistep surgery including liver transplantation. Introduction of FOLFIRINOX after relapse repeatedly achieved a durable metabolic and clinical response with good quality of life.

Abstract

Pancreatic tumors are rare in children and adolescents. Here, we report the case of a 15-year-old boy who presented with a mixed acinar cell carcinoma/ductal adenocarcinoma with blastomatous components. He received multimodal treatment including various chemotherapy regimens and multistep surgery including liver transplantation. Introduction of FOLFIRINOX after relapse repeatedly achieved a durable metabolic and clinical response with good quality of life.

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Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
04 Faculty of Medicine > University Hospital Zurich > Institute of Pathology and Molecular Pathology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Nuclear Medicine
04 Faculty of Medicine > University Hospital Zurich > Clinic for Visceral and Transplantation Surgery
04 Faculty of Medicine > University Hospital Zurich > Clinic for Gastroenterology and Hepatology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Oncology and Hematology
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Health Sciences > Oncology
Uncontrolled Keywords:Acinar cell carcinoma, Autologous stem cell transplantation, Ductal adenocarcinoma, FOLFIRINOX, Multimodal treatment, Pancreatic cancer, Pancreatoblastoma
Language:English
Date:2013
Deposited On:08 Nov 2013 08:17
Last Modified:24 Jan 2022 01:58
Publisher:Karger
ISSN:1662-6575
OA Status:Gold
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1159/000355320
PubMed ID:24163668
  • Content: Published Version
  • Language: English
  • Licence: Creative Commons: Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0)