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Milleret, Vincent; Simona, Benjamin R; Lienemann, Philipp S; Vörös, János; Ehrbar, Martin (2014). Electrochemical control of the enzymatic polymerization of peg hydrogels: formation of spatially controlled biological microenvironments. Advanced Healthcare Materials, 3(4):508-514.
Control of pH gradient profile at the electrode-electrolyte interfaces allows the control of the enzymatic PEG-hydrogel polymerization. By tuning the solution pH, buffer capacity, and the applied current, the extent of the local inhibition and confinement of the Factor XIII-mediated polymerization of PEG are controlled. This technology opens new perspectives for the production of 3D-structured biological microenvironments.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > University Hospital Zurich > Clinic for Obstetrics
04 Faculty of Medicine > Institute of Biomedical Engineering |
| Dewey Decimal Classification: | 170 Ethics
610 Medicine & health |
| Scopus Subject Areas: | Physical Sciences > Biomaterials
Physical Sciences > Biomedical Engineering Life Sciences > Pharmaceutical Science |
| Uncontrolled Keywords: | Pharmaceutical Science, Biomaterials, Biomedical Engineering |
| Language: | English |
| Date: | 2014 |
| Deposited On: | 22 Nov 2013 15:52 |
| Last Modified: | 10 Jan 2025 02:39 |
| Publisher: | Wiley-Blackwell |
| ISSN: | 2192-2640 |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1002/adhm.201300479 |
| PubMed ID: | 24574303 |
Milleret, Vincent