Villalgordo, Jose M; Heimgartner, Heinz (1993). A Novel Synthesis of 2,2-Disubstituted 3-Amino-2H-azirines Based on the Reaction between Amide Enolates and Diphenyl Phosphorochloridate. Helvetica Chimica Acta, 76:2830-2837.
A novel synthesis of 2,2-disubstituted 3-amino-2H-azirines based on the reaction between amide enolates and diphenyl phosphorochloridate (DPPCI), followed by treatment with NaN3 is presented. The yields obtained in general are excellent, and the method is suitable for laboratory-scale preparations as well as for larger amounts.
A novel synthesis of 2,2-disubstituted 3-amino-2H-azirines based on the reaction between amide enolates and diphenyl phosphorochloridate (DPPCI), followed by treatment with NaN3 is presented. The yields obtained in general are excellent, and the method is suitable for laboratory-scale preparations as well as for larger amounts.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 07 Faculty of Science > Department of Chemistry |
| Dewey Decimal Classification: | 540 Chemistry |
| Uncontrolled Keywords: | Physical and Theoretical Chemistry, Inorganic Chemistry, Organic Chemistry, Biochemistry, Drug Discovery, Catalysis |
| Language: | English |
| Date: | 1993 |
| Deposited On: | 26 Dec 2013 09:29 |
| Last Modified: | 24 Sep 2019 19:53 |
| Publisher: | Wiley-Blackwell |
| ISSN: | 0018-019X |
| Funders: | Swiss National Science Foundation, F. Hoffmann-La Roche AG, Basel |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1002/hlca.19930760809 |
| Project Information: |
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Villalgordo, Jose M