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Villalgordo, Jose M; Heimgartner, Heinz (1993). A Novel Synthesis of 2,2-Disubstituted 3-Amino-2H-azirines Based on the Reaction between Amide Enolates and Diphenyl Phosphorochloridate. Helvetica Chimica Acta, 76:2830-2837.
A novel synthesis of 2,2-disubstituted 3-amino-2H-azirines based on the reaction between amide enolates and diphenyl phosphorochloridate (DPPCI), followed by treatment with NaN3 is presented. The yields obtained in general are excellent, and the method is suitable for laboratory-scale preparations as well as for larger amounts.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 07 Faculty of Science > Department of Chemistry |
| Dewey Decimal Classification: | 540 Chemistry |
| Scopus Subject Areas: | Physical Sciences > Catalysis
Life Sciences > Biochemistry Life Sciences > Drug Discovery Physical Sciences > Physical and Theoretical Chemistry Physical Sciences > Organic Chemistry Physical Sciences > Inorganic Chemistry |
| Uncontrolled Keywords: | Physical and Theoretical Chemistry, Inorganic Chemistry, Organic Chemistry, Biochemistry, Drug Discovery, Catalysis |
| Language: | English |
| Date: | 1993 |
| Deposited On: | 26 Dec 2013 09:29 |
| Last Modified: | 10 Mar 2025 02:39 |
| Publisher: | Wiley-Blackwell |
| ISSN: | 0018-019X |
| Funders: | Swiss National Science Foundation, F. Hoffmann-La Roche AG, Basel |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1002/hlca.19930760809 |
| Project Information: |
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Villalgordo, Jose M