Abstract
A camphor-based alpha'-hydroxy enone reagent acts as a chiral acrylate equivalent in copper-catalyzed Michael reactions of beta-keto esters and affords products that possess all-carbon quaternary stereocenters of high enantiomeric purity.
Palomo, C; Oiarbide, M; García, J M; Bañuelos, P; Odriozola, J M; Razkin, J; Linden, Anthony (2008). Catalytic Michael reactions of ketoesters with a camphor-derived acrylate equivalent: stereoselective access to all-carbon quaternary centers. Organic Letters, 10(13):2637-2640.
Abstract
A camphor-based alpha'-hydroxy enone reagent acts as a chiral acrylate equivalent in copper-catalyzed Michael reactions of beta-keto esters and affords products that possess all-carbon quaternary stereocenters of high enantiomeric purity.
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Additional indexing
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 07 Faculty of Science > Department of Chemistry |
| Dewey Decimal Classification: | 540 Chemistry |
| Scopus Subject Areas: | Life Sciences > Biochemistry
Physical Sciences > Physical and Theoretical Chemistry Physical Sciences > Organic Chemistry |
| Language: | English |
| Date: | 2008 |
| Deposited On: | 19 Jan 2009 16:03 |
| Last Modified: | 23 Jan 2022 12:50 |
| Publisher: | American Chemical Society |
| ISSN: | 1523-7052 |
| Funders: | Universidad del Paı´s Vasco, Gobierno Vasco, MEC, UPNA |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1021/ol800564d |
| PubMed ID: | 18517215 |
Palomo, C