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Osteogenesis Imperfecta Type II: Fetal Magnetic Resonance Imaging Findings


Solopova, A; Wisser, J; Huisman, T A (2008). Osteogenesis Imperfecta Type II: Fetal Magnetic Resonance Imaging Findings. Fetal Diagnosis and Therapy, 24(4):361-367.

Abstract

We describe the prenatal magnetic resonance imaging (MRI) findings in a 25-week-old fetus with proven osteogenesis imperfecta type II. Fetal MRI findings are correlated with prenatal ultrasonography, conventional x-ray fetography and postpartal findings. Fetal MRI proves to be superior to conventional fetography in the evaluation of the skeletal findings. The high soft tissue resolution, the large field of view and the multiplanar imaging make it possible to study the non-ossified fetal skeleton in detail. Compared to prenatal ultrasonography, fetal MRI gives important additional information about the expected lung functionality by estimating fetal lung volume and signal intensity and rules out possible additional abnormalities of major fetal organs. These parameters may serve as valuable, additional prognostic markers in the prenatal diagnostic work-up.

Abstract

We describe the prenatal magnetic resonance imaging (MRI) findings in a 25-week-old fetus with proven osteogenesis imperfecta type II. Fetal MRI findings are correlated with prenatal ultrasonography, conventional x-ray fetography and postpartal findings. Fetal MRI proves to be superior to conventional fetography in the evaluation of the skeletal findings. The high soft tissue resolution, the large field of view and the multiplanar imaging make it possible to study the non-ossified fetal skeleton in detail. Compared to prenatal ultrasonography, fetal MRI gives important additional information about the expected lung functionality by estimating fetal lung volume and signal intensity and rules out possible additional abnormalities of major fetal organs. These parameters may serve as valuable, additional prognostic markers in the prenatal diagnostic work-up.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Obstetrics
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Health Sciences > Pediatrics, Perinatology and Child Health
Health Sciences > Embryology
Health Sciences > Radiology, Nuclear Medicine and Imaging
Health Sciences > Obstetrics and Gynecology
Language:English
Date:2008
Deposited On:07 Jan 2009 16:58
Last Modified:02 Dec 2023 02:36
Publisher:Karger
ISSN:1015-3837
OA Status:Green
Publisher DOI:https://doi.org/10.1159/000163447
PubMed ID:18931501
  • Content: Published Version