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Genome sequence of Streptococcus mutans bacteriophage M102


van der Ploeg, J R (2007). Genome sequence of Streptococcus mutans bacteriophage M102. FEMS Microbiology Letters, 275(1):130-138.

Abstract

Bacteriophage M102 is a lytic phage specific for serotype c strains of Streptococcus mutans, a causative agent of dental caries. In this study, the complete genome sequence of M102 was determined. The genome is 31,147 bp in size and contains 41 ORFs. Most of the ORFs encoding putative phage structural proteins show similarity to those from bacteriophages from Streptococcus thermophilus. Bioinformatic analysis indicated that the M102 genome contains an unusual lysis cassette, which encodes a holin and two lytic enzymes.

Abstract

Bacteriophage M102 is a lytic phage specific for serotype c strains of Streptococcus mutans, a causative agent of dental caries. In this study, the complete genome sequence of M102 was determined. The genome is 31,147 bp in size and contains 41 ORFs. Most of the ORFs encoding putative phage structural proteins show similarity to those from bacteriophages from Streptococcus thermophilus. Bioinformatic analysis indicated that the M102 genome contains an unusual lysis cassette, which encodes a holin and two lytic enzymes.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > Center for Dental Medicine > Institute of Oral Biology
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Life Sciences > Microbiology
Life Sciences > Molecular Biology
Life Sciences > Genetics
Language:English
Date:October 2007
Deposited On:20 Mar 2009 10:42
Last Modified:29 Jul 2020 17:10
Publisher:Wiley-Blackwell
ISSN:0378-1097
Additional Information:The definitive version is available at www.blackwell-synergy.com.
OA Status:Hybrid
Publisher DOI:https://doi.org/10.1111/j.1574-6968.2007.00873.x
PubMed ID:17711456

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