Moch, Holger; Lukamowicz-Rajska, Magdalena (2014). miR-30c-2-3p and miR-30a-3p: New pieces of the Jigsaw puzzle in HIF2α regulation. Cancer Discovery, 4(1):22-24.
Summary: Clear cell renal cell carcinoma (ccRCC), the most frequent subtype of renal cell cancer, is characterized by mutation of the von Hippel-Lindau (VHL) tumor suppressor gene, which results in stabilization of hypoxia-inducible factor (HIF) α proteins. In this issue of Cancer Discovery, Mathew and colleagues report that miR-30c-2-3p and miR-30a-3p downregulation in ccRCC promotes increased expression of HIF2α.Cancer Discov; 4(1); 22-4. ©2014 AACR.
Summary: Clear cell renal cell carcinoma (ccRCC), the most frequent subtype of renal cell cancer, is characterized by mutation of the von Hippel-Lindau (VHL) tumor suppressor gene, which results in stabilization of hypoxia-inducible factor (HIF) α proteins. In this issue of Cancer Discovery, Mathew and colleagues report that miR-30c-2-3p and miR-30a-3p downregulation in ccRCC promotes increased expression of HIF2α.Cancer Discov; 4(1); 22-4. ©2014 AACR.
| Item Type: | Journal Article, refereed, further contribution |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > University Hospital Zurich > Institute of Pathology and Molecular Pathology |
| Dewey Decimal Classification: | 610 Medicine & health |
| Scopus Subject Areas: | Health Sciences > Oncology |
| Language: | English |
| Date: | 2014 |
| Deposited On: | 24 Mar 2014 13:58 |
| Last Modified: | 24 Jan 2022 03:39 |
| Publisher: | American Association for Cancer Research |
| ISSN: | 2159-8274 |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1158/2159-8290.CD-13-0897 |
| PubMed ID: | 24402943 |
Moch, Holger