Header

UZH-Logo

Maintenance Infos

Coherent diffraction and holographic imaging of individual biomolecules using low-energy electrons


Latychevskaia, Tatiana; Longchamp, Jean-Nicolas; Escher, Conrad; Fink, Hans-Werner (2013). Coherent diffraction and holographic imaging of individual biomolecules using low-energy electrons. In: Read, Randy; Urzhumtsev, Alexandre G; Lunin, Vladimir Y. Advancing Methods for Biomolecular Crystallography. Dordrecht: Springer, 331-342.

Abstract

Modern microscopy techniques are aimed at imaging an individual molecule at atomic resolution. Here we show that low-energy electrons with kinetic energies of 50–250 eV offer a possibility of overcome the problem of radiation damage, and obtaining images of individual biomolecules. Two experimental schemes for obtaining images of individual molecules – holography and coherent diffraction imaging – are discussed and compared. Images of individual molecules obtained by both techniques, using low-energy electrons, are shown.

Abstract

Modern microscopy techniques are aimed at imaging an individual molecule at atomic resolution. Here we show that low-energy electrons with kinetic energies of 50–250 eV offer a possibility of overcome the problem of radiation damage, and obtaining images of individual biomolecules. Two experimental schemes for obtaining images of individual molecules – holography and coherent diffraction imaging – are discussed and compared. Images of individual molecules obtained by both techniques, using low-energy electrons, are shown.

Statistics

Citations

Dimensions.ai Metrics

Altmetrics

Downloads

2 downloads since deposited on 27 Feb 2014
0 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Book Section, refereed, original work
Communities & Collections:07 Faculty of Science > Physics Institute
Dewey Decimal Classification:530 Physics
Scopus Subject Areas:Physical Sciences > General Chemistry
Life Sciences > Biochemistry, Genetics and Molecular Biology (miscellaneous)
Physical Sciences > Safety, Risk, Reliability and Quality
Language:English
Date:2013
Deposited On:27 Feb 2014 08:34
Last Modified:30 Jul 2020 12:58
Publisher:Springer
Series Name:NATO Science for Peace and Security Series A: Chemistry and Biology
ISBN:978-94-007-6231-2
OA Status:Closed
Publisher DOI:https://doi.org/10.1007/978-94-007-6232-9_29

Download

Closed Access: Download allowed only for UZH members