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Jenny, Christjohannes; Heimgartner, Heinz (1986). Synthese von 4,4-disubstituierten 1,3-ThiazoI-5(4H)-thionen. Helvetica Chimica Acta, 69(2):374-388.
An easy synthesis for the 1,3-thiazol-5(4H)-thiones 5, a class of heterocycles which have hitherto only been available with difficulty, is described. Reaction of 3-amino-2H-azirines 25 with thiocarboxylic acids at 0° yields monothiodiamides of type 20 (Scheme 6) which, on treatment with Lawesson reagent at 100°, undergo thiation and cyclization to give 5 in good yield.
| Other titles: | Synthesis of 4,4-Disubstituted 1,3-Thiazol-5(4H)-thiones |
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| Item Type: | Journal Article, refereed, original work |
| Communities & Collections: | 07 Faculty of Science > Department of Chemistry |
| Dewey Decimal Classification: | 540 Chemistry |
| Scopus Subject Areas: | Physical Sciences > Catalysis
Life Sciences > Biochemistry Life Sciences > Drug Discovery Physical Sciences > Physical and Theoretical Chemistry Physical Sciences > Organic Chemistry Physical Sciences > Inorganic Chemistry |
| Uncontrolled Keywords: | Physical and Theoretical Chemistry, Inorganic Chemistry, Organic Chemistry, Biochemistry, Drug Discovery, Catalysis |
| Language: | German |
| Date: | 1986 |
| Deposited On: | 04 Jun 2014 08:09 |
| Last Modified: | 11 Mar 2025 02:38 |
| Publisher: | Wiley-Blackwell |
| ISSN: | 0018-019X |
| Funders: | Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung, F. Hoffmann-La Roche & Co. AG, Basel, Stipendienfonds der Schweizerischen Chemischen Industrie |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1002/hlca.19860690217 |
| Project Information: |
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Jenny, Christjohannes